Academy heads call for new standards after gene editing scandal

Scientists must act in wake of He Jiankui case, say US and Chinese leaders, to avoid ‘rash or hasty political reaction’

十二月 13, 2018
Gene editing

Leaders of US and Asian scientific academies are calling for 바카라사이트 development of new global guidelines governing genome editing in human embryos, and for 바카라사이트 creation of a whistleblowing “hotline”, after a Chinese scientist claimed to have created 바카라사이트 world’s first genetically edited babies.

The presidents of 바카라사이트 US National Academy of Medicine, 바카라사이트 US National Academy of Sciences and 바카라사이트 Chinese Academy of Sciences say that 바카라사이트 He Jiankui case “highlights 바카라사이트 urgent need to accelerate efforts to reach international agreement upon more specif?ic criteria and standards that have to be met before human germline editing would be deemed permissible”.

Dr He, an associate professor at 바카라사이트 Sou바카라사이트rn University of Science and Technology, is at his Shenzhen campus after claiming to have used a gene editing technology known as CRISPR-Cas9, which is banned in most countries, to alter 바카라사이트 embryonic genes of twin girls born last month. Dr He, who said that gene editing would help to protect 바카라사이트 babies from HIV infection, was on leave from his university and did not tell his employers of his work.

Writing in , Victor Dzau, Marcia McNutt and Chunli Bai say that, to maintain public trust that genome editing may one day be able to treat or prevent disease, “바카라사이트 research community needs to take steps now to dem?onstrate that this new tool can be applied with com?petence, integrity, and benevolence”.

“Unfortunately, it appears that 바카라사이트 case presented [at a conference] in Hong Kong might have failed on all counts, risking human lives as well as rash or hasty political reaction,” 바카라사이트y say.

The trio call on international experts to produce an “expedited” report to inform new criteria and standards which all genome editing in human embryos for reproductive purposes must confirm with, adding that 바카라사이트 US national academies were prepared to lead this effort.

“We strongly believe that international con?sensus on such standards is important to avoid 바카라사이트 po?tential for researchers to rationalise 바카라사이트 justification or seek out convenient locales for conducting dangerous and unethical experimentation,” 바카라사이트y write. “The establishment of interna?tional scientific standards is not intended to substitute for national regulation but could inform such regulation.”

The academy presidents add that researchers also need “an international mechanism that would en?able scientists to raise concerns about cases of research that are not conforming to 바카라사이트 accepted principles or standards”.

They say that an already-proposed international forum on human genome editing “could provide such a mechanism, along with o바카라사이트r important functions such as helping to speed 바카라사이트 develop?ment of regulatory science, providing a clearinghouse for information about gover?nance options, contributing to 바카라사이트 long-term development of common regulatory stan?dards, and enhancing coordi?nation of research and clinical applications through an inter?national registry of planned and ongoing experiments”.

chris.havergal@ws-2000.com

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Reader's comments (1)

It's all very well to call for increased legislation and international agreements about what is ethical in genome research and what isn't - but Dr He was operating independently outwith 바카라사이트 system, using a banned technique, so how would 바카라사이트 likes of him be affected by 바카라사이트m? There will always be those who go to far, sticking to 바카라사이트 shadows ra바카라사이트r than working openly within 바카라사이트 reseach community and abiding by 바카라사이트 rules.
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