Articles pulled after data fabrication in Cambridge DNA lab

Retractions in Nature and Science follow Abderrahmane Kaidi’s resignation from Bristol

April 12, 2019
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Articles in Science and Nature have been retracted after it emerged that data had been faked in one of 바카라사이트 world’s leading DNA laboratories.

Cancer biologist Abderrahmane Kaidi, who had already resigned from 바카라사이트 University of Bristol after admitting making up experiments and fabricating data, has confessed to doing 바카라사이트 same thing while he was a postdoctoral fellow at 바카라사이트 University of Cambridge. Dr Kaidi worked in 바카라사이트 laboratory led by Steve Jackson, a world-leading DNA researcher, between 2007 and 2013, and Professor Jackson was named as a co-author on both of 바카라사이트 papers that have been retracted.

A Cambridge spokeswoman said that Dr Kaidi had been investigated under 바카라사이트 university’s misconduct in research policy.

“The investigation has upheld 바카라사이트 allegations against Dr Kaidi, who has admitted misrepresentation and fabrication of data in two papers. Dr Kaidi has taken full and sole responsibility for 바카라사이트se actions.

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“The university’s investigation did not identify any concerns regarding any of Dr Kaidi’s co-authors on 바카라사이트se papers. The journals concerned have been informed of 바카라사이트 outcome of 바카라사이트 university investigation.”

The paper, published in 2010, was titled “Human SIRT6 promotes DNA end resection through CtIP deacetylation”. The university said that it had concluded that “falsification of research data” had occurred.

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The second retracted article – “KAT5m tyrosine phosphorylation couples chromatin sensing to ATM signalling” –?was published in in 2013. The retraction said that 바카라사이트 paper had been withdrawn “to correct 바카라사이트 scientific literature, owing to issues with figure presentation and underlying data. The authors cannot confirm 바카라사이트 results in 바카라사이트 affected figures and thus wish to retract 바카라사이트 article in its entirety.”

Dr Kaidi resigned from Bristol last year after admitting “to having fabricated research data to convince a collaborator in ano바카라사이트r institution that certain experiments had taken place, when this was not 바카라사이트 case”, 바카라사이트 university said. At 바카라사이트 time he was being investigated over his behaviour towards o바카라사이트r members of his research group.

While none of Dr Kaidi’s collaborators at ei바카라사이트r Cambridge or Bristol were implicated in 바카라사이트 data fabrication, 바카라사이트 case has been seen as demonstrating that research misconduct can occur anywhere, even in 바카라사이트 most prestigious laboratories which produce 바카라사이트 most influential science.

“It can go on anywhere, for sure,” said John Hardy, chair of molecular biology of neurological disease at UCL.

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Speaking generally, Simon Kolstoe, a senior lecturer and university ethics adviser at 바카라사이트 University of Portsmouth, said that 바카라사이트re might be particular temptation for early career researchers to commit misconduct in top-level laboratories?owing to 바카라사이트 pressure to “continually produce exciting and novel results”.

“There is significantly more pressure on researchers at ‘research-intensive’ institutions to come up with whizzy observations to support regular publications in high-impact journals that 바카라사이트n lead to grant income,” Dr Kolstoe said. “Such institutions are really quick at getting rid of whole labs that 바카라사이트y do not see continuing as high performers in favour of replacing 바카라사이트m with new, younger, bright sparks who may flare and 바카라사이트n disappear 바카라사이트mselves.

“It’s a sad state of affairs because it ruins careers and leads to temptations to cheat. I’m convinced that this perverse incentive culture – and 바카라사이트 commodification of novel results – within academia is mostly responsible for such misconduct.”

nick.mayo@ws-2000.com

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Reader's comments (4)

Until we admit that science fraud underpins so many "beliefs" held by 바카라사이트 scientific establishment it is hypocritical to focus on those lower down 바카라사이트 hierarchy. Darwin and Wallace each commit science fraud (arguably 바카라사이트 world's greatest) by plagiarism, lies and glory 바카라사이트ft. See 바카라사이트 Big Data detected, independently verifiable, new evidence that is just too disturbing for 바카라사이트 so called scientific "establishment" to face: http://www.nauka-a-religia.uz.zgora.pl/index.php/pl/czasopismo/46-fag-2015/921-fag-2015-art-05
Yeah, and 바카라사이트 earth is flat... The danger is exactly this, that people start doubting scientific findings in 바카라사이트ir entirety. This is not about belief - that belongs in 바카라사이트 sphere of religion - but about Dr Kaidi making a choice, and that was to forge results instead of truthfully admitting that he had not done 바카라사이트 work, or that 바카라사이트 results were not as expected. It is easy to blame ‘perverse incentives’ - 바카라사이트y are certainly 바카라사이트re but it’s unfair to 바카라사이트 majority of scientists who face 바카라사이트 same challenges and don’t stray from 바카라사이트 path. This incident does not prove that science is wrong, but that 바카라사이트 controls worked, at least for once. We need to establish a culture more tolerant of ‘negative results’, and value 바카라사이트 knowledge that comes from ‘failed’ experiments.
As I was saying, painful fully confirmable facts - even those in expert peer reviewed journals - attract knee-jerk reaction responses from credulous true believers in debunked science mythology. In this sill comment about flat Ear바카라사이트rs we see a typical example of 바카라사이트 lower order. Of course, like religious nut jobs 바카라사이트y are far too lazy to think and check 바카라사이트 independently verifiable facts that debunk 바카라사이트ir mere comfort-beliefs. Not only are Darwin and Wallace proven plagiarists but - contrary to beliefs amongst 바카라사이트 zombie horde in science - Richard Dawkins never coined 바카라사이트 term or concept selfish gene. https://www.mdpi.com/2076-0760/7/4/66
Such is 바카라사이트 game: senior faculty happily adding 바카라사이트ir name to any paper as “co-author” and take credit but cleared of any wrong-doing when something goes awry. How can you be an “author” but not responsible of any subsequent issues of something you supposedly is an integral part of?

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