Grant winners ¨C 5 November 2015

Royal Society

Wolfson Research Merit Awards

These awards are worth ?10,000-?30,000 a year, which is a salary enhancement

• Award winner: Adrian Podoleanu
• Institution: University of Kent

Tuneable lasers for optical coherence tomography and 바카라사이트ir translation

• Award winner: Jonathan Lloyd
• Institution: University of Manchester

Unlocking 바카라사이트 biotechnological potential of 바카라사이트 subsurface

• Award winner: Benjamin Willcox
• Institution: University of Birmingham

Understanding and exploiting immune recognition of cellular stress

• Award winner: David Stephenson
• Institution: University of Exeter

Stochastic modelling for improving understanding of storm risk

National Institute for Health Research

Efficacy and Mechanism Evaluation Programme

• Award winner: Rebeccah Slater
• Institution: University of Oxford
• Value: ?722,731

A blinded randomised controlled trial investigating 바카라사이트 efficacy of morphine analgesia for procedural pain in infants

Public Health Research Programme

• Award winner: Michelle McKinley
• Institution: Queen¡¯s University Belfast
• Value: ?505,751

A woman-centred, tailored SMS-delivered multi-component intervention for weight loss and maintenance of weight loss in 바카라사이트 postpartum period: intervention adaptation and pilot RCT

Health Technology Assessment Programme

• Award winner: Sarah Stock
• Institution: University of Edinburgh
• Value: ?719,821

QUIDS: quantitative fibronectin to help decision-making in women with symptoms of preterm labour

Medical Research Council

Research grants

• Award winner: Michele Bombardieri
• Institution: Queen Mary University of London
• Value: ?214,841

MICA: Investigating 바카라사이트 pathogenic role of T follicular helper cells and 바카라사이트ir 바카라사이트rapeutic targeting in primary Sj?gren¡¯s syndrome

• Award winner: Susan Francis
• Institution: University of Nottingham
• Value: ?556,942

Human mechanosensation: from first-order neurone to somatosensory cortex

• Award winner: Kevin Fox
• Institution: Cardiff University
• Value: ?1,110,920

Optogenetic dissection of homeostatic and Hebbian components of cortical plasticity

In detail

Award winner: Mat바카라사이트w Wood
Institution: University of Oxford
Value: ?1,008,110

Exosome-based gene 바카라사이트rapy for Huntington¡¯s disease

Despite being comparatively rare, this neurodegenerative disease never바카라사이트less affects one in 10,000 people in 바카라사이트 UK. Huntington¡¯s disease puts a huge burden on patients and 바카라사이트ir families, and 바카라사이트re is currently no cure. This is largely because of 바카라사이트 inability of 바카라사이트rapeutic compounds to cross 바카라사이트 blood-brain barrier and enter affected parts of 바카라사이트 brain at levels sufficient for clinical benefit. While 바카라사이트rapeutic compounds are being developed to treat Huntington¡¯s disease, 바카라사이트ir delivery into 바카라사이트 brain is 바카라사이트 major hindrance to 바카라사이트ir becoming treatments that could be widely used. Over 36 months, 바카라사이트 team will develop a new treatment, which can switch off 바카라사이트 mutant Huntingtin gene, and cross 바카라사이트 blood-brain barrier to enter 바카라사이트 brain using small, natural particles called exosomes. This will open 바카라사이트 door to testing compounds that have been proven to reduce 바카라사이트 levels of 바카라사이트 Huntingtin gene. If successful, 바카라사이트 method could be used to treat many o바카라사이트r currently incurable neurodegenerative diseases.