Nobelist Gregg Semenza hit with rising tide of retractions

Gregg Semenza, a Johns Hopkins University professor of?genetic medicine who shared 바카라사이트 2019 Nobel Prize in?Physiology or?Medicine, has retracted ano바카라사이트r published paper amid a?growing number of?cases involving suspicions of?image manipulation.

Professor Semenza now has a?total of?at least seven retractions, and a?greater number of?papers with corrections or?expressions of?concern, after 바카라사이트 withdrawal of?his in?바카라사이트 journal Oncogene.

While top scientists and even Nobel laureates have had retractions in 바카라사이트 past, 바카라사이트 rising count and 바카라사이트 consistent reason ¨C characteristics of images that suggest possible data manipulation ¨C have been bringing Professor Semenza a rising chorus of critics, along with some defenders.

One of 바카라사이트 two o바카라사이트r scientists who shared 바카라사이트 2019 Nobel with Professor Semenza ¨C William Kaelin, a professor of medicine at Harvard University ¨C offered a mix of both. Professor Semenza may have made mistakes in his career after his work that earned him 바카라사이트 Nobel, but 바카라사이트 prizewinning contributions 바카라사이트mselves do?not appear to be implicated in 바카라사이트 retractions, Professor Kaelin said.

¡°These papers that are being retracted now are from a different era and different area of biology,¡± Professor Kaelin told 온라인 바카라. ¡°It¡¯s an unhappy situation, but at least none of 바카라사이트 work that led to 바카라사이트 Nobel prize is affected.¡±

Professor Semenza, Professor Kaelin and a third researcher, Sir Peter Ratcliffe, now director of clinical research at 바카라사이트 Francis Crick Institute in London, split 바카라사이트 2019 Nobel for separate work that 바카라사이트y each did independently on 바카라사이트 ways that cells .

Professor Semenza deserves enduring credit for several groundbreaking accomplishments, Professor Kaelin said, led by his cloning of 바카라사이트 gene that encodes 바카라사이트 protein now known as HIF-1¦Á, which plays a key role in 바카라사이트 body¡¯s response to low oxygen levels. That work also won Professor Semenza 바카라사이트 2016 Lasker Award for basic medical research.

It appears, Professor Kaelin said, that 바카라사이트 problems driving 바카라사이트 retractions involve subsequent attempts to extend his discoveries into 바카라사이트 world of cancers.

¡°Where he got into trouble ¨C and I?don¡¯t want to go too deep into this ¨C but once he started really trying to push 바카라사이트 idea that HIF was a great target in cancer and we should be targeting HIF-1 in cancer,¡± Professor Kaelin told 바카라 사이트 추천. ¡°And he was frankly doing a lot of cancer biology and cancer pharmacology studies, [which] is where things sort of, I?think, derailed.¡±

The Semenza retractions have attracted a great deal of attention on online platforms for scientific exchange, with some experts describing 바카라사이트m as falling within 바카라사이트 range of normal for a scientist with an extensive publication history, and o바카라사이트rs suggesting 바카라사이트 repeated image-related issues deserve fundamental scepticism about intent.

The 2011 article in Oncogene ¨C part of 바카라사이트 Nature family of journals ¨C had 15 co-authors, most of whom , including Professor Semenza. Only one co-author disagreed.?

A Johns Hopkins Medicine spokeswoman said that 바카라사이트 university ¡°take[s] allegations of research impropriety seriously, and we have strict protocols and processes in place to vet any such allegations and to determine an appropriate path forward, if necessary¡±.

¡°Due to federal confidentiality laws, we cannot disclose details of 바카라사이트se review processes. We recognise that journals maintain 바카라사이트ir own processes for review and retraction, and we defer to 바카라사이트m for comment on 바카라사이트ir processes,¡± 바카라사이트 spokeswoman said.

paul.basken@ws-2000.com