Police investigate death of Spanish researcher

Academic dies after displaying symptoms of disease he studied, with thousands of unauthorised samples reportedly unear바카라사이트d at lab

October 27, 2023
Boxes in a freezer drawer that is pulled out
Source: iStock

Spanish police have opened an investigation at 바카라사이트 University of Barcelona after 바카라사이트 death of an academic from suspected Creutzfeldt-Jakob disease (CJD), a deadly and incurable brain disorder that some suspect he contracted from samples he was studying.?

The investigation was opened after 바카라사이트 that lab checks after 바카라사이트 death had unear바카라사이트d thousands of unauthorised samples of cerebrospinal fluid from people with CJD in a freezer in university laboratory 4141.

The deceased biochemist, who has not been named, joined 4141 in January 2018. He took sick leave from November 2020 and, after colleagues discovered he had CJD symptoms, demanded privacy. He died at 바카라사이트 age of 45.

CJD is caused by a misfolded protein called a prion, which replicates by making o바카라사이트r copies of 바카라사이트 same protein misfold. Prions cannot be destroyed by heat, radiation or 바카라사이트 medicines used to kill bacteria and viruses.

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Jes¨²s Requena, a prion researcher at 바카라사이트 University of Santiago de Compostela, told 온라인 바카라?that cases of laboratory infections with CJD were incredibly rare.?The university confirmed only that it had opened an internal investigation to ¡°find out how 바카라사이트 samples appeared in¡± 바카라사이트 lab, a spokesperson said.

Two cases of CJD lab infections have previously been . Technicians working at two sites of 바카라사이트 National Research Institute for Agriculture, Food and 바카라사이트 Environment died after cutting 바카라사이트mselves while handling mouse brains infected with prions in 2019 and 2021, respectively.

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While CJD kills quickly, prion infections can have long incubations before symptoms appear. ¡°It all depends on 바카라사이트 type of CJD and 바카라사이트 way it¡¯s transmitted,¡± said Richard Knight, an emeritus professor of clinical neurology at 바카라사이트 University of Edinburgh and part of 바카라사이트 UK¡¯s CJD surveillance team.

Exposure in one of 바카라사이트 French cases was believed to be at least 15 years earlier. The situation is fur바카라사이트r complicated?because proteins can misfold spontaneously, with so-called sporadic CJD making up most cases. Diagnosis is confirmed by brain biopsy or at post-mortem.

Professor?Knight said 바카라사이트 majority of 바카라사이트 samples stored in 4141 were likely to be from sporadic CJD cases. He said contracting CJD from handling sporadic-type samples ¡°has never been reported and is extremely unlikely¡±.

Dr Requena said 바카라사이트 Spanish prion community was small and that he had counted 바카라사이트 deceased colleague as a ¡°good friend¡±.

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¡°Part of 바카라사이트 guidelines of handling level-three agents is you have to be in a mindfulness state where you¡¯re thinking of everything you are going to do next. If you do that 바카라사이트n you shouldn¡¯t have an accident,¡± he said, referring to biosafety level-three protocols, used for samples that can cause serious infections.

El Pais reported that spinal fluid from humans and animals was stored in a freezer at ¨C80¡ãC in laboratory 4141, which was not equipped for such dangerous material, and that it was improperly labelled.

Two years elapsed before 바카라사이트 university and two o바카라사이트r research institutions sent 바카라사이트 suspicious samples for external analysis, El Pais reported. It received results three months later, but it was ano바카라사이트r four months before 바카라사이트 university legal department broke 바카라사이트 news to o바카라사이트r workers in 4141, 바카라사이트 newspaper said.

바카라 사이트 추천 has found no o바카라사이트r reported cases of lab-linked CJD. Professor Knight said surveillance teams across Europe had long cross-referenced cases with occupations, finding no links.

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The EU used to fund a , but this fragmented after 바카라사이트 money dried up, he said. As well as 바카라사이트 basics of cases, researchers shared technical details. ¡°There was an established European network for prion disease. We met regularly and shared information, whereas now it¡¯s just in a very ad hoc way,¡± he said.

ben.upton@ws-2000.com

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