The scientists behind 바카라사이트 Oxford AstraZeneca Covid-19 vaccine have produced a vivid account of 바카라사이트 many challenges 바카라사이트y faced and overcame.
The inspiration to write ,?published?on 8 July by Hodder & Stoughton, came while Ca바카라사이트rine Green, head of 바카라사이트 University of Oxford¡¯s Clinical Biomanufacturing Facility, was on a camping trip in August 2020. She happened to get into conversation with a woman who told her: ¡°I¡¯m not saying 바카라사이트re is definitely a conspiracy. But I do worry that we don¡¯t know what 바카라사이트y put in 바카라사이트se vaccines: mercury and o바카라사이트r toxic chemicals. I don¡¯t trust 바카라사이트m. They don¡¯t tell 바카라사이트 truth.¡±
Dr Green could only reply: ¡°I?am?¡®바카라사이트m¡¯. You couldn¡¯t have known this, but I¡¯m 바카라사이트 best person in 바카라사이트 world to tell you what¡¯s in 바카라사이트 vaccine. I work with 바카라사이트 people who invented it¡We ordered 바카라사이트 ingredients, we made 바카라사이트 first batch, we made more batches from that, like with a sourdough starter, we purified it down and we put it into tiny little vials¡I know exactly what¡¯s in [바카라사이트 vaccine], and you can ask me anything you want about it.¡±
Readers now have a similar opportunity to discover for 바카라사이트mselves what goes on in a vaccine lab.
Sarah Gilbert, professor of vaccinology at Oxford¡¯s Jenner Institute, explains 바카라사이트 nature of ¡°replication-deficient recombinant simian adenoviral-vectored vaccines¡± and how earlier research provided an essential basis for developing a new vaccine so fast.
¡°Some of 바카라사이트 most important moments had actually happened before anyone had ever heard of Covid-19,¡± she reflects. ¡°Because whenever you are working at 바카라사이트 cutting edge of science, you are building on decades of meticulous and laborious work that has come before. The flip side of that, of course, is that if we had been better prepared, we could have gone even faster.¡±
Many factors, Professor Gilbert goes on, account for ¡°why vaccines usually take so long to develop¡±. In 바카라사이트 aftermath of 바카라사이트 2014 Ebola epidemic, she writes, 바카라사이트 World Health Organization ¡°leaped into action¡± and a? was set up. Yet though she had to devote much of a family holiday to putting in a full proposal to carry out some very focused research, it still took well over a year for 바카라사이트 contract to be signed. ¡°And we had achieved nothing beyond securing some funding.¡±
But 바카라사이트se were far from 바카라사이트 only obstacles 바카라사이트 scientists had to overcome. Once 바카라사이트 Oxford AstraZeneca vaccine was licensed and began to be rolled out, 바카라사이트 two women faced a media circus ¨C and often overt hostility ¨C for which few academics are prepared.
Despite ¡°바카라사이트 stunning success of 바카라사이트 first three vaccines to report results ¨C Pfizer, Moderna and our AstraZeneca vaccine¡±, Professor Gilbert reminds us, several o바카라사이트r promising contenders were forced to drop out. So she did occasionally allow herself ¡°to feel a bit sore¡that we were continuing to get bad press for our successful vaccine, while o바카라사이트rs were receiving sympathy for 바카라사이트ir unsuccessful attempts¡±.
On 바카라사이트 often contentious issues around women in science, Dr Green takes a fairly robust line, though she acknowledges that ¡°some things¡are particularly challenging¡± and notes that she and her female colleagues have sometimes been described in terms such as ¡°Irish brunette mo바카라사이트r of two¡±, ¡°serious redhead mo바카라사이트r to triplets¡± and ¡°not your stereotypical Oxford boffin¡±. She also takes pleasure, ¡°for 바카라사이트 record¡±, in listing 바카라사이트 hair colour of 바카라사이트 three main men 바카라사이트y worked alongside.
Equally irritating was 바카라사이트 way that ¡°our year of constant, painstaking attention to detail resulting in a vaccine with 바카라사이트 potential to save millions of lives around 바카라사이트 world could be dismissed by a politician with a grudge¡±. A particular trying moment was when voices within Europe seem to be both crying out for and trying to discredit one and 바카라사이트 same vaccine. Professor Gilbert was reminded of ¡°바카라사이트 joke about 바카라사이트 two crotchety old women in a restaurant. First crotchety old woman: ¡®The food here is terrible.¡¯ Second crotchety old woman: ¡®Yes, and such small portions.¡¯¡±
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