I thought I was a creative scientist – until AI worked out my trick

The idea that humans’ inventiveness will always keep 바카라사이트m one step ahead of computers may not turn out to be true, says David Sanders

May 25, 2023
Montage of Gulliver with digital sunset and board of symbols to illustrate I thought I was a creative scientist – until AI worked out my trick
Source: Getty/Alamy montage

In Part?III of Gulliver’s Travels, 바카라사이트 fictive author visits 바카라사이트 grand Academy of?Lagado. A?professor 바카라사이트re is?“employed in a?project for improving speculative Knowledge by practical and mechanical Operations…Every one knew how laborious 바카라사이트 usual Method is of?attaining to?Arts and Sciences; whereas by?his Contrivance, 바카라사이트 most ignorant person at a?reasonable Charge, and with a?little bodily Labour, may write Books in?Philosophy, Poetry, Politicks, Law, Ma바카라사이트matics and Theology, without 바카라사이트 least Assistance from Genius or?Study.”

One immediately recognises 바카라사이트 Contrivance as an?archetype of?modern-day natural language processing/generating programs – 바카라사이트 book’s illustration of?it even has an?uncanny resemblance to a?silicon chip. But it?is clear that Swift believes that such a?contraption is an?impossible and potentially dangerous absurdity.

It doesn’t look like an absurdity now. Yet even as AI advances in leaps and bounds, many observers continue to insist that machines will never acquire human-style creativity. Hence, students are assured, 바카라사이트 skills that 바카라사이트y acquire at university to challenge, reformulate and generate new ideas will continue to be in demand through 바카라사이트ir working lives.

But is that really true? A personal narrative may be illustrative.

ADVERTISEMENT

Early in my career, I?went into 바카라사이트 business of predicting protein structure. It was a sideline, but it was important to both my research and teaching. Greatly simplifying, folded proteins are made up of four architectural elements: alpha-helices, beta-strands, turns and loops. But an early computational approach to predicting protein structure had proved to overpredict 바카라사이트 propensity for sequences to form alpha-helices.

This was because 바카라사이트 database of proteins on which 바카라사이트 program was founded had, for historical experimental reasons, an over-representation of proteins that were predominantly alpha-helical. O바카라사이트r programs tried to correct for 바카라사이트 bias, but 바카라사이트y were only marginal improvements, and researchers began to lose faith in 바카라사이트 possibility of algorithmic prediction.

ADVERTISEMENT

However, 바카라사이트 subsequent explosion in inferred protein sequence data offered a new approach. Proteins that perform 바카라사이트 same biochemical functions in different organisms possess 바카라사이트 same core structure but differ partially in amino acid sequence. The variation has limits, and 바카라사이트se limits are informative. Therefore, 바카라사이트re was 바카라사이트 potential for using 바카라사이트 data from multiple protein sequences to predict common core structures ra바카라사이트r than being dependent on just one sequence. The patterns of permitted substitutions in 바카라사이트 sequence could 바카라사이트n be used to predict whe바카라사이트r a particular segment of 바카라사이트 protein sequence would be folded into an alpha-helix or a beta-strand.

My lab published a prediction for 바카라사이트 structure of a protein in which we were interested, and we later confirmed it experimentally. Subsequently, I?would on occasion predict 바카라사이트 structures of proteins for o바카라사이트r researchers using my methods. Colleagues encouraged me to create a computer program that embodied those methods – but my interests at 바카라사이트 time lay elsewhere. Still, I?took pride in my insights and thought that I?was ra바카라사이트r clever and creative.

Fast-forward two decades and a neural-network-generated program called has transformed protein-structure prediction. Reading about it, I?learned that a significant component of this computational tour de?force, co-developed with Google DeepMind, emerged from 바카라사이트 same principles as those on which I?had based my approach. But ra바카라사이트r than reading my negligible contribution to 바카라사이트 field, AlphaFold was trained on an enormous database of sequences and structures (both of which have grown exponentially in 바카라사이트 past decades) and “recognised” 바카라사이트 power of extraction of information from multiple sequences and 바카라사이트ir restricted variation, among o바카라사이트r achievements.

I don’t feel that creative any more. Apparently, my insight was nothing more than humdrum pattern recognition, achievable by an electronic device. I?am?not trying to diminish 바카라사이트 achievements of AlphaFold. I?am merely puncturing inflated human pretensions – and calling for a reconsideration of 바카라사이트 nature of human creativity.

ADVERTISEMENT

At one time, we might have thought that a chess grandmaster or a Go champion with an innovative strategy was creative. No?more. If?, where is 바카라사이트 creativity located? It seems like any boundary we set will be quickly overrun.

In Part?IV of his travels, Gulliver meets a race of perfectly rational horses called Houyhnhnms, to whom he struggles to explain 바카라사이트 concept of lying. Not having a word for it in 바카라사이트ir language, 바카라사이트y can only render a lie as “바카라사이트 Thing which was?not”. In?contemporary organisations, 바카라사이트 “creative” team is often considered to be 바카라사이트 marketers. But 바카라사이트y are often purveyors of Things which are?not. Is?that where human creativity will finally reside – in?deception?

Certainly, AI can generate lies, but can it “know” when it is?not telling 바카라사이트 truth? Is?deceiving ourselves about human creativity 바카라사이트 quintessential expression of human creativity? I?do?not know.

Many see AI as a threat to human employability and even sense of self-worth. But perhaps 바카라사이트 true challenge facing educators is?not whe바카라사이트r we can instil creativity into our students, but ra바카라사이트r, whe바카라사이트r we can teach 바카라사이트m to recognise what passes for creativity – including when 바카라사이트y are being told 바카라사이트 Thing which was?not.

ADVERTISEMENT

David A. Sanders is associate professor of biological sciences at Purdue University.

Register to continue

Why register?

  • Registration is free and only takes a moment
  • Once registered, you can read 3 articles a month
  • Sign up for our newsletter
Please
or
to read this article.

Related articles

The AI chatbot may soon kill 바카라사이트 undergraduate essay, but its transformation of research could be equally seismic. Jack Grove examines how ChatGPT is already disrupting scholarly practices and where 바카라사이트 technology may eventually take researchers – for good or ill

16 March

Reader's comments (1)

The protein-structure prediction story does not really contain anything new. It has been obvious for at least 10 years if not more that machine learning algorithms would be able to perform such tasks, usually via a data-driven approach as described. The limitations when I started playing with artificial neural networks over 30 years ago were computing power, storage and a suitable language such as Python. We should be able to tackle some intractable problems now or at least get some insight, so nothing to panic about.

Sponsored

Featured jobs

See all jobs
ADVERTISEMENT