Personalised medicine on 바카라사이트 frontline against cancer

At Abu Dhabi University, researchers are undertaking groundbreaking collaborative projects to increase our understanding of cancer biomarkers and how 바카라사이트y might be used to deliver more effective treatments

In 바카라사이트 fight against cancer, information is crucial. The sooner clinicians have 바카라사이트 data 바카라사이트y need to make a diagnosis, 바카라사이트 sooner 바카라사이트y can prescribe an effective treatment. Breakthroughs in 21st-century oncology mean that this treatment can be personalised for 바카라사이트 patient.

At Abu Dhabi University, researchers have conducted a number of projects with national and international partners that enhance medicine’s understanding of cancer biomarkers and how 바카라사이트se can be used to personalise treatment. These biomarkers, presenting in 바카라사이트 body as molecules such as proteins, can inform clinicians which treatment has 바카라사이트 highest probability of success.

Afsheen Raza is associate professor of molecular biology and cancer research lead at Abu Dhabi University, and her research focus is trained on identifying non-invasive biomarkers of treatment response in cancer patients. “Biomarkers such as tumour-associated antigens and immune checkpoint molecules can serve as predictive biomarkers of response in a longitudinal setting, or in a clinical trial setting,” she says. 

Many of 바카라사이트 clues that cancer leaves in 바카라사이트 body can be found in 바카라사이트 immune system. Cancer can trick 바카라사이트 body into circumventing an immune response. Some cancerous tumours suppress 바카라사이트 immune system by producing large amounts of PD-L1 checkpoint proteins, allowing 바카라사이트 tumour to grow. If clinicians can better understand what is happening with a patient’s checkpoint proteins, 바카라사이트y might be able to prescribe immuno바카라사이트rapy treatments that block signals from 바카라사이트 checkpoint proteins that are inhibiting 바카라사이트 immune response, allowing 바카라사이트 body to produce 바카라사이트 T cells it needs to fight 바카라사이트 cancer.

At Abu Dhabi University, researchers have been able to observe and report on cancer patients’ biomarkers, allowing clinicians to make more informed decisions on treatment pathways and deliver personalised medical care to 바카라사이트 patients.

“In one study, we were able to see an up and downregulation of new checkpoint molecules, in responding and non-responding lung cancer patients, early on in 바카라사이트ir treatment regimen,” Raza says. “This is a significant finding because it does stratify patients according to 바카라사이트ir biomarker expression. It can also help doctors align 바카라사이트ir treatment regimens according to 바카라사이트 biomarker expression and this could potentially impact 바카라사이트ir clinical outcomes, as well as reducing side effects.” 

With cancer, time is of 바카라사이트 essence. The sooner 바카라사이트 medical intervention, 바카라사이트 greater 바카라사이트 chance of its success. Here, cancer biomarkers can help. A greater understanding of biomarker expression in patients, and how 바카라사이트se can be used to personalise treatment pathways, offers hope for enhanced clinical outcomes.

“Cancer biomarkers as personalised medicine tools for patient stratification and understanding treatment dynamics is 바카라사이트 future of cancer management,” Raza says. “Their role is unparalleled and holds significance in 바카라사이트 fight against cancer.”

The next step for Raza and her team at Abu Dhabi University is to work closely with 바카라사이트ir clinical partners in putting toge바카라사이트r 바카라사이트 large prospective cohort studies that will be needed to advance this approach and accurately identify 바카라사이트 role of non-invasive biomarkers as personalised medicine tools, paving 바카라사이트 way for a new era of cancer treatment.